Category Archives: Coronavirus

ACE Inhibitors Not a Risk Factor for #COVID19 #Coronavirus

Probably at little risk of serious illness if she’s generally healthy

Early on in this pandemic, there was concern that people taking ACE inhibitor drugs for hypertension would be more prone to infection from the coronavirus SARS-CoV-2. From two new studies in NEJM:

In this large, population-based study, the use of ACE inhibitors and ARBs was more frequent among patients with Covid-19 than among controls because of their higher prevalence of cardiovascular disease. However, there was no evidence that ACE inhibitors or ARBs affected the risk of COVID-19.

Source: Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19 | NEJM

We found no substantial increase in the likelihood of a positive test for Covid-19 or in the risk of severe Covid-19 among patients who tested positive in association with five common classes of antihypertensive medications [including ACE inhibitors and ARBs].

Source

 

QOTD: Schlichter on #Coronavirus, Police Lawlessness, Rioting, and Self-Defense

No rule of law here. It’s the law of the jungle.

The Chinese coronavirus fiasco, the shocking killing of George Floyd, and the riots resulting from Democrat failure have taught the American people several things. One is that a surprising and sad number of law enforcement officers are willing to follow cheesy, stupid, and unconstitutional orders. A quick tour of social media will horrify you with the damage done to that support by video of stupid cops hassling civilians for going outside or trying to attend church. The people who long backed the blue feel stabbed in the back, and LEOs are going to have to work to earn back the support they lost because a lot of their comrades sided with Democrat bullies against the people.

Similarly, we have learned that the police are not necessarily going to be there for us. From that gooey tub of cowardice in Florida who let kids be murdered while he stood with a weapon outside the school – I can’t even type those words without sputtering in rage – to the MPD [Minneapolis Police Department] running away and letting criminals burn their building, do you feel comfortable putting your lives in the hands of such government employees? The one inspirational sight during the riots was a bunch of black Americans with modern rifles defending their businesses.

Four in Ten of All U.S. #COVID19 Deaths Were in Elder Care Facilities #Coronavirus

Are you tired of this pic yet?

I’ve reported here before that shockingly high rates of COVID-19 deaths in elder care facilities in a few individual states. Avik Roy looked at data from multiple states:

Roy writes in Forbes:

According to an analysis that Gregg Girvan and I conducted for the Foundation for Research on Equal Opportunity, as of May 22, in the 43 states that currently report such figures, an astounding 42% of all COVID-19 deaths have taken place in nursing homes and assisted living facilities.

*  *  *

And 42% could be an undercount. States like New York exclude from their nursing home death tallies those who die in a hospital, even if they were originally infected in a long-term care facility. Outside of New York, more than half of all deaths from COVID-19 are of residents in long-term care facilities.

 *  *  *

Nearly one-tenth of all New Jersey long-term care residents have died from COVID-19

As I recall, the first COVID-19 outbreak in the U.S. was in a nursing home in Kirkland, Washington.

Do you ever wonder how this pandemic could have been less severe if our rulers had concentrated their public health efforts on elder care facilities and older vulnerable adults? I do.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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Handy Chart of When States Went Into Panic Mode #COVID19 #Coronavirus

I’ve been an advocate of opening up the economy since April 2, 2020. So if millions more in the U.S. die from COVID-19 you’ll know who to blame, partially. Of course, if my recommendations are followed, few will perish.

Despite my following the pandemic fairly closely, I couldn’t remember exactly when the Arizona economy was strangled. The handy chart below indicates March 31, 2020. For you states that don’t return to relative freedom and  capitalism, don’t ask the rest of us for a bailout. You made your bed, now lie in it.

Steve Parker, M.D.

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Is There a Role For Zinc in Treatment or Prevention of #COVID19? #Coronavirus

Artist’s rendition of Coronavirus

Read the article in Advances in Nutrition and then let me know in the comment section:

ABSTRACT

Zinc is an essential trace element that is crucial for growth, development, and the maintenance of immune function. Its influence reaches all organs and cell types, representing an integral component of approximately 10% of the human proteome, and encompassing hundreds of key enzymes and transcription factors. Zinc deficiency is strikingly common, affecting up to a quarter of the population in developing countries, but also affecting distinct populations in the developed world as a result of lifestyle, age, and disease-mediated factors. Consequently, zinc status is a critical factor that can influence antiviral immunity, particularly as zinc-deficient populations are often most at risk of acquiring viral infections such as HIV or hepatitis C virus. This review summarizes current basic science and clinical evidence examining zinc as a direct antiviral, as well as a stimulant of antiviral immunity. An abundance of evidence has accumulated over the past 50 y to demonstrate the antiviral activity of zinc against a variety of viruses, and via numerous mechanisms. The therapeutic use of zinc for viral infections such as herpes simplex virus and the common cold has stemmed from these findings; however, there remains much to be learned regarding the antiviral mechanisms and clinical benefit of zinc supplementation as a preventative and therapeutic treatment for viral infections.

Source: Role of Zinc in Antiviral Immunity | Advances in Nutrition | Oxford Academic

#COVID19 Fallout: U.S. Unemployment Rate Up to Almost 15%

The U.S. economy

As expected, everyone ignored my April 2 advice to open up the economy and let healthy, relatively young people go back to work. Read on, and weep.

Unemployment rates were higher in April in all 50 states and the District ofColumbia, the U.S. Bureau of Labor Statistics reported today. Similarly, all 50 states and the District had jobless rate increases from a year earlier.

The national unemployment rate rose by 10.3 percentage points over the month to 14.7 percent and was 11.1 points higher than in April 2019.

*  *  *

Nevada had the highest unemployment rate in April, 28.2 percent, followed by Michigan, 22.7 percent, and Hawaii, 22.3 percent. The rates in 43 states set new series highs. (All state series begin in 1976.)

I can understand the devastating unemployment numbers for Nevada and Hawaii; they’re heavy into travel and tourism. Michigan? I don’t know.

Source: State Employment and Unemployment Summary

Steve Parker, M.D.

PS: I live in Arizona. Our unemployment rate is 12.6%.

Steve Parker MD, Advanced Mediterranean Diet

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From Ivor Goodbody: Major Risk Factors for Death From #COVID19 #Coronavirus

Probably at little risk of serious illness if she’s generally healthy

Note that a prior diagnosis of hypertension (high blood pressure) was NOT a risk factor for death from COVID-19. Most other coronavirus articles list hypertension as a risk factor for serious illness, if not death, from COVID-19. Admittedly, “serious illness” is not the same as death. I’ve never understood how chronically controlled hypertension could increase risk of serious illness or death.

I recently read someone calling coronavirus, instead, controlavirus. Referring to governments controlling our businesses, personal movements, shopping practices, access to “non-essential” services, and violating our constitutional rights to peaceably assemble and worship as we choose. Not as our rulers choose.

“Return to your home and hide under your bed!”

Steve Parker, M.D.

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Should Andrew Cuomo Be Charged With Manslaughter?

It’s looking like, nationally, 30-40% of COVID-19 deaths in the U.S. are of nursing home residents, whether they perished at the nursing home or contracted the disease there and died in the hospital. The percentage varies from state to state.

From Daily Caller:

New York nursing homes were forced to accept more than 4,500 coronavirus patients from hospitals thanks to an order from Democratic New York Gov. Andrew Cuomo, a tally by The Associated Press found.

Cuomo has come under heated criticism for his March 25 order forcing recovering COVID-19 patients into New York nursing homes — a decision blamed for the state’s high body count among the elderly. The governor waited roughly six weeks before reversing the order on May 10.

The New York State Department of Health refused to release the results of an internal survey on how many coronavirus patients were placed in nursing homes across the state, the AP reported.

The health department is knowingly under-counting the number of nursing home deaths as a result of a quiet rule change made in late April, a department spokesman previously acknowledged following a Daily Caller News Foundation investigation

Steve Parker, M.D.

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NYT: Lockdowns Are Not at All New #COVID19 #Coronavirus

I’ve slipped into the questionable habit of using “social distancing” and “lockdown” interchangeably. The latter is more politically charged and is perhaps best used to describe the more draconian forms of social distancing.

The April 22, 2020, article is by Eric Lipton and Jennifer Steinhauer:

Dr. Markel had published a book, “When Germs Travel,” in 2004 that examined six major epidemics since 1900 and how they had traveled across the United States. He decided to work with Dr. Martin S. Cetron, the director of the C.D.C.’s quarantine division, to look more closely at the lessons of the Spanish flu of 1918.

The research started with St. Louis, which had moved relatively quickly to head off the spread of the flu, and Philadelphia, which waited much longer and suffered far more.

Officials in Philadelphia did not want to let the flu disrupt daily life, so they went ahead in September 1918 with a long planned paradethat drew hundreds of thousands of spectators to promote war bonds.

In St. Louis, by contrast, the city health commissioner quickly moved to close schools, churches, theaters, saloons, sporting events and other public gathering spots.

Dr. Markel and his team set out to confirm just how important a role timing had played in reducing deaths. They gathered census records and thousands of other documents detailing the date of the first infection, the first death, the first social distancing policies and how long they were left in place in 43 American cities.

Separately, Dr. Mecher and his team looked at the experience of 17 cities, using newspaper clips and other sources.

Both teams came to the same conclusion and published papers on their findings within months of each other in 2007. Early, aggressive action to limit social interaction using multiple measures like closing schools or shutting down public gatherings was vital to limiting the death toll, they found.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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#Coronavirus, #CytokineStorm, #YellowFever, and #Lockdown

From Richard Fernandez at PJ Media:

One of the ways the Coronavirus kills is by stimulating an overreaction of a patient’s own immune system. “Diseases such as covid-19 and influenza can be fatal due to an overreaction of the body’s immune system called a cytokine storm.”

This metaphor can also describe how society can harm itself  when measures taken to control a disease do more harm than good. Perhaps the most forceful and controversial reaction to the coronavirus epidemic has been the lockdown, which believe it or not, did not exist in the American context as a bureaucratic concept before 2006.

   The rest of the story is at The New York Times:

Fourteen years ago, two federal government doctors, Richard Hatchett and Carter Mecher, met with a colleague at a burger joint in suburban Washington for a final review of a proposal they knew would be treated like a piñata: telling Americans to stay home from work and school the next time the country was hit by a deadly pandemic.

When they presented their plan not long after, it was met with skepticism and a degree of ridicule by senior officials, who like others in the United States had grown accustomed to relying on the pharmaceutical industry, with its ever-growing array of new treatments, to confront evolving health challenges.

Drs. Hatchett and Mecher were proposing instead that Americans in some places might have to turn back to an approach, self-isolation, first widely employed in the Middle Ages.

How that idea — born out of a request by President George W. Bush to ensure the nation was better prepared for the next contagious disease outbreak — became the heart of the national playbook for responding to a pandemic is one of the untold stories of the coronavirus crisis

So today’s “lockdown” and “social distancing” have the same origin. Actually, lockdown is an older term referring to locking incarcerated convicts into their cells, as might be necessary to gain control of a riot or after an escape. Some of you are starting to feel like convicts.

Little noted by the mainstream media are the medical definitions of quarantine and isolation. From the CDC:

Isolation and quarantine help protect the public by preventing exposure to people who have or may have a contagious disease.

    • Isolation separates sick people with a contagious disease from people who are not sick.
    • Quarantine separates and restricts the movement of people who were exposed to a contagious disease to see if they become sick.

Isolating ourselves to avoid exposure to infection is not the same as the CDC’s  isolation.

I lived in Pensacola, FL, for twelve years. While there I learned about the scourge of deadly Yellow Fever. It’s a viral infection that had migrated from West Africa and is transmitted to humans by mosquitos. It’s not a problem in Florida anymore since we have control of the mosquito population. But earlier, many of the rich folks in Pensacola would move up north during the hot summer months—mosquito season—to escape from the virus. That was probably even before we knew mosquitos were the vector. They just knew when it was hot and humid, Yellow Fever was rampant. I don’t recall exactly where “up north” was, but I’m guessing the southern reaches of the Appalachian mountains in Alabama and Georgia. The wealthy summer migrants weren’t infected, but were self-isolating, in the non-medical sense of the term. Like New Yorkers migrating to the Hamptons or Florida to escape the ‘rona.

Steve Parker, M.D.

PS: Pepe Escobar writes that Dr Hatchett was a proponent lockdown earlier than 14 years ago:

Enter Dr. Richard Hatchett, a former member of the National Security Council during the first Bush Jr. administration, who was already recommending obligatory confinement of the whole population way back in 2001. Hatchett now directs the Coalition for Epidemic Preparedness Innovations (CEPI), a very powerful entity coordinating global vaccine investment, and very cozy with Big Pharma. CEPI happens to be a brainchild of the WEF [World Economic Forum] in conjunction with the Bill and Melinda Gates Foundation.

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