QOTD: George Washington on Foreign Entanglements

“George Washington (Porthole type), Rembrandt“/ CC0 1.0

The great rule of conduct for us in regard to foreign nations is in extending our commercial relations, to have with them as little political connection as possible. So far as we have already formed engagements, let them be fulfilled with perfect good faith. Here let us stop. Europe has a set of primary interests which to us have none; or a very remote relation. Hence she must be engaged in frequent controversies, the causes of which are essentially foreign to our concerns. Hence, therefore, it must be unwise in us to implicate ourselves by artificial ties in the ordinary vicissitudes of her politics, or the ordinary combinations and collisions of her friendships or enmities.

Our detached and distant situation invites and enables us to pursue a different course. If we remain one people under an efficient government, the period is not far off when we may defy material injury from external annoyance; when we may take such an attitude as will cause the neutrality we may at any time resolve upon to be scrupulously respected; when belligerent nations, under the impossibility of making acquisitions upon us, will not lightly hazard the giving us provocation; when we may choose peace or war, as our interest, guided by justice, shall counsel.

Why forego the advantages of so peculiar a situation? Why quit our own to stand upon foreign ground? Why, by interweaving our destiny with that of any part of Europe, entangle our peace and prosperity in the toils of European ambition, rivalship, interest, humor or caprice?

It is our true policy to steer clear of permanent alliances with any portion of the foreign world; so far, I mean, as we are now at liberty to do it; for let me not be understood as capable of patronizing infidelity to existing engagements. I hold the maxim no less applicable to public than to private affairs, that honesty is always the best policy. I repeat it, therefore, let those engagements be observed in their genuine sense. But, in my opinion, it is unnecessary and would be unwise to extend them. . . .

Source

Are Microplastics Really All That Bad?

“Free pile plastic bottles image“/ CC0 1.0

Sabine Hossenfelder says maybe. But we don’t know for sure. From around February, 2026:

The Man in the Arena (video)

Scattered Pandemic Thoughts: Two Comedians and a Proven Conspiracy

artist's rendition of coronavirus
Artist’s rendition of Coronavirus

John Wilder wrote a funny retrospective on the recent pandemic. Can you believe it started way back six and a half years ago? (I had occasion to order tocilizumab recently for a cancer patient and had forgotten it was part of our armamentarium against COVID-19.)

It starts thusly:

I thought that I had done my last post on COVID.  I really did.

Then, that pisspot troll smugboi Fauci went before Congress and put on the most pathetic, weasel-like performance I’ve ever seen.  As perhaps is his right, he pled the Fifth Amendment to avoid answering any question asked, including revealing such secrets as the color of the carpet or the color of his tie.

—–Steve Parker, M.D.

PS: Comedienne Leonarda Jonie remembers the pandemic.

PPS: Dr. John Campbell reports on a former senior NIAID (National Institute of Allergy and Infectious Diseases) official who pled guilty to concealing federal records during the pandemic. The charges were related to conspiracy to evade Freedom of Information Act (FOIA) requests and the Federal Records Act in connection with communications about coronavirus research grants. The conspirator is David M. Morens, 78. There is mention of an unnamed co-conspirator. Could that be Fauci?

I Bet Salvatore Isn’t Following the Traditional Mediterranean Lifestyle

salmon, salad, mediterranean diet, fish, meal, dinner
Greek salad with canned salmon. Salmon is one of the cold-water fatty fish.

Thanks to Jan at The Low Carb Diabetic for turning me on to this BBC article:

Daily life is not easy for Salvatore. At 17, he weighs 170kg [375 lb] and struggles to walk.

He can’t tie his own shoelaces and his Vespa scooter strains to bear his weight – in one week, its wheels broke seven times. 

“He eats constantly,” says his mother Anna. 

Salvatore is among a growing number of Italian children and teenagers living with obesity. The problem is particularly acute in the south: in parts of the Campania region, more than 40% of eight and nine-year-olds are overweight. The town of Ponticelli, on the outskirts of Naples, has earned the unenviable reputation as one of the world’s child obesity capitals. 

It is a striking development in a country long regarded as the spiritual home of the Mediterranean diet. Yet today, Italian children are among the most overweight in Europe, according to the World Health Organization (WHO).

RTWT.

—–Steve Parker, M.D.

Is Adjuvant Chemotherapy Worth the Risk?

Dr. Jonathan Storey at Science Based Medicine:

Her recent breast surgery went perfectly. The tumor is out, margins are clear, and none of her scans show any cancer. So, she is understandably distraught when I begin to discuss the option of chemotherapy. “But I thought they got it all,” she says.

As a medical oncologist, I have had some version of this conversation hundreds of times, but it never gets easier. We call it adjuvant therapy — the medical practice of giving a person four to six months of chemotherapy after their cancer surgery, just in case. The underlying logic of adjuvant therapy rests on a single uncomfortable fact.

The practice of oncology is hard. I hope you never have to make a decision regarding adjuvant chemotherapy.

—–Steve Parker, M.D.

PS: There is a way of eating linked to lower risk of getting cancer. See below.

Hope or Hype: Ivermectine and Mebendazole as Cancer Treatment

But it’s horse de-wormer!

You can read about this (or watch the video) at various places. One is TheFocalPoints.com.

“84.4% of Cancer Patients Taking Ivermectin + Mebendazole Reported No Evidence of Disease, Tumor Regression, or Cancer Stabilization After 6 Months”

It just sounds too good to be true. And you know want that usually means. I’ve not done a deep dive into this report but I’m very skeptical. The study lumped a bunch of different cancer types together: breast, pancreas, colon, lung, etc. The uneducated among us may think all cancers are alike. They are not. They behave differently and, traditionally, require different therapeutic approaches for the best outcome. If (and that’s a big IF) there is a unifying underlying chemical or cellular phenomenon that causes all cancers, then a panacea like ivermectin/mebendazole may be an effective treatment. (In case you’re wondering, I was prepared to take ivermectin during the pandemic but never did.)

Just a reminder, I am not a cancer specialist. If I had cancer, I would consult a cancer specialist, typically an oncologist.

Authors of the study at hand do note that “…these findings should be interpreted as hypothesis-generating. Urgent prospective, randomized, placebo-controlled clinical trials are warranted to validate these observations and further define optimal dosing strategies.” You may recognize one of the authors, TV celebrity Dr. Drew Pinsky. What a Renaissance man! Other familiar author names are Peter McCullough and Harvey Risch.

Dr. David Weinberg at Science Based Medicine has done a deep dive and concluded:

This is a shoddy research study presented as a quality improvement project. This dubious classification functioned as an excuse for lack of interface with relevant regulatory bodies.

There is validity to the assertion that ivermectin and mebendazole show anticancer activity in preclinical studies. This study provides no meaningful evidence for or against the efficacy of such treatments in humans with cancer.  

—–Steve Parker, M.D.

PS: Reduce your risk of getting cancer with the Mediterranean diet!

Omega-3 Supplements: Brain Poison or Dementia Preventative?

I recently started taking an omega-3 fish oil supplement with hopes of preserving cognitive function as I age. Cold-water fatty fish are a natural source of omega-3s and I haven’t been eating much lately. My supplement contains 1040 mg of omega-3 fatty acids. It’s a large pill that is difficult to swallow sometimes.

Alaskan Omega-3 Fish Oil by Sports Research

Now I’m starting to wonder if I should continue. From Daily Mail:

The [single observational study] researchers compared 273 people who take omega-3 supplements daily, with 546 similar non-users – and found that those taking fish-oil pills appeared to decline faster on several cognitive scores.

However…

…when it comes to omega 3s and cognitive function, in a major [meta-analysis] review published recently in Scientific Reports, analysis of 58 randomised controlled trials from multiple countries suggested that omega-3 supplements may be associated with slightly better cognitive outcomes – or slower decline in some areas, particularly memory.

Steve Parker, M.D.

Baby Boomers Not as Healthy as Previous Generation

From The Guardian:

Researchers analysed health data for more than 100,000 people between 2004 and 2018, covering several generations of people aged 50 and above across England, the US and Europe.

Photo by Isabel Ponce on Pexels.com

They found increasing rates of chronic disease, especially when comparing people born between 1936 and 1945 and those born from 1955 to 1959.

Rates of chronic disease rose across successive generations in all regions, with more recently born adults more likely to have cancer, lung disease, heart issues, type 2 diabetes and high cholesterol than their predecessors at the same age.

Although prevalence of type 2 diabetes rose at the same rate across all regions, diagnoses of cancer, heart problems and high cholesterol increased the most in England and Europe, with baby boomers and people in their 50s being 1.5 times more likely to have these issues than their predecessors at the same age.

Levels of grip strength, a good measure of overall muscle strength and healthy ageing, decreased across generations in England and the US, but either increased or remained constant in Europe.

Why is health worse?

Pollution? Poor food quality? Increasing rates of obesity? Increasing social isolation? Over-crowding? Loss of religion?

—–Steve Parker, M.D.

Dogman on America’s Obesity

This guy is a raconteur. He also vlogs at Ouchita Mountain Living.

—–Steve Parker, M.D.