Category Archives: prediabetes

Prediabetes May Not Be a Meaningful Diagnosis for those over 70


When physicians identify a patient as having prediabetes, we usually tell them they are at increased risk for actual diabetes in the next few years, and recommend steps that should reduce the risk of progression. A recent study of older folks (average age 76) suggests the risk of progression isn’t very high. In fact the odds are greater for a return to normal blood sugars, or death. The report is a little confusing because the authors used two definitions of prediabetes.

Question:  What is the risk of progression to diabetes among older adults with prediabetes (based on glycated hemoglobin level of 5.7%-6.4%, fasting glucose levels of 100-125 mg/dL, either, or both) in a community-based population?

Findings:  In this cohort study of 3412 older adults, the prevalence of prediabetes (mean [SD] age, 75.6 [5.2] years) was high and differed substantially depending on the definition used, with estimates ranging from 29% for glycated hemoglobin levels of 5.7% to 6.4% and fasting glucose levels of 100 to 125 mg/dL to 73% for either glycated hemoglobin levels of 5.7% to 6.4% or fasting glucose levels of 100 to 125 mg/dL. During the 6 years of follow-up, death or regression to normoglycemia from prediabetes was more frequent than progression to diabetes.

Meaning:  Prediabetes may not be a robust diagnostic entity in older age.

Source: Risk of Progression to Diabetes Among Older Adults With Prediabetes | Geriatrics | JAMA Internal Medicine | JAMA Network

Steve Parker, M.D.

Prediabetes Is Way Too Common in the Youth of U.S.A.

I’m worried about the kid’s future health

Stats from JAMA Pediatrics:

In the United States, about 1 of 5 adolescents [12–18 y.o.] and 1 of 4 young adults [19–34 y.o.] have prediabetes. The adjusted prevalence of prediabetes is higher in male individuals and in people with obesity. Adolescents and young adults with prediabetes also present an unfavorable cardiometabolic risk profile, putting them both at increased risk of type 2 diabetes and cardiovascular diseases.

Source: Prevalence of Prediabetes Among Adolescents and Young Adults in the United States, 2005-2016. – PubMed – NCBI

I’m doing my part to prevent conversion of prediabetes to type 2 diabetes. The right diet, exercise, and weight loss are just what the doctor ordered.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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