Early on in this pandemic, there was concern that people taking ACE inhibitor drugs for hypertension would be more prone to infection from the coronavirus SARS-CoV-2. From two new studies in NEJM:
In this large, population-based study, the use of ACE inhibitors and ARBs was more frequent among patients with Covid-19 than among controls because of their higher prevalence of cardiovascular disease. However, there was no evidence that ACE inhibitors or ARBs affected the risk of COVID-19.
We found no substantial increase in the likelihood of a positive test for Covid-19 or in the risk of severe Covid-19 among patients who tested positive in association with five common classes of antihypertensive medications [including ACE inhibitors and ARBs].