Tag Archives: telomere length

Telomere length and the cancer-atherosclerosis trade-off 

Telomeres are a hot research area now. If you can keep your telomeres long, you may live longer. But that may be an oversimplification. Click the link below for details. A teaser:

“Telomeres are caps of tandem repeats of DNA that protect the ends of all chromosomes. They are implicated in ageing because, with successive bouts of cell division, they are gradually whittled away to expose chromosomes to damage and, eventually, an inability to replicate any further. Sarah Tishkoff, together with co-authors Rivka Stone and Abraham Aviv, from the New Jersey Med School, and several others, have been taking a hard look at the evolution of telomere length across species and human groups and argue that there is a direct relationship between telomere length and susceptibility to cancer and atherosclerosis (and other diseases of ageing). Specifically, they describe evidence for an evolutionary trade-off whereby shorter telomeres in some human groups protect against cancer but expose individuals to a greater risk of other diseases in later life.”

Source: Telomere length and the cancer – atherosclerosis trade-off – The Evolution and Medicine Review