Higher Risk of Death in China From #COVID19 #Coronavirus Linked to Age, Diabetes, Hypertension, Coronary Artery Disease, and COPD

Artist’s rendition of coronavirus

The Lancet published a report on the outcomes of Coronavirus (COVID-19) infection in two Wuhan, China, hospitals as of Jan 31, 2020.

  • Those who died of the infection had higher rates of hypertension, diabetes, coronary artery disease and COPD (chronic obstructive pulmonary disease.
  • Average age of those who died was 69. Survivors’ average age was 52.
  • Men were more likely to be hospitalized than women.

Details from the report:

191 patients (135 from Jinyintan Hospital and 56 from Wuhan Pulmonary Hospital) were included in this study, of whom 137 were discharged and 54 died in hospital. 91 (48%) patients had a comorbidity, with hypertension being the most common (58 [30%] patients), followed by diabetes (36 [19%] patients) and coronary heart disease (15 [8%] patients). Multivariable regression showed increasing odds of in-hospital death associated with older age (odds ratio 1·10, 95% CI 1·03–1·17, per year increase; p=0·0043), higher Sequential Organ Failure Assessment (SOFA) score (5·65, 2·61–12·23; p<0·0001), and d-dimer greater than 1 μg/mL (18·42, 2·64–128·55; p=0·0033) on admission. Median duration of viral shedding was 20·0 days (IQR 17·0–24·0) in survivors, but SARS-CoV-2 was detectable until death in non-survivors. The longest observed duration of viral shedding in survivors was 37 days.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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