Have You Been Wiping Your Ass Wrong All These Years?

This is a topic I’d never run across online until recently. In the anal hygeine department, it looks like the Europeans and Japanese—with their bidets—are ahead of us in North America.

From Insider:

To keep your backside happy, Goldstein [a rectal surgeon] recommended using a patting motion rather than a wiping motion and being as gentle as possible. Ideally, he added, you should use a bidet to clean yourself and then pat the excess water dry with a bit of toilet paper if need be.

From MF (Mental Floss):

Asbury [a dermatologist] is an advocate of the standalone or add-on toilet accessory that squirts a spray of water between your cheeks to flush out residual fecal matter. While bidets are common in Europe and Japan, the West has been slower to adopt this superior method of post-poop clean-up; others might be wary of tapping into existing home plumbing to supply fresh water, even though DIY installation is quite easy. For those patients, Asbury has developed an alternative method.

TRY PAPER TOWELS AND WATER

“What I tell people to use is Viva, a really soft, thick paper towel made by Kleenex,” he says. “You get a squirt bottle and you leave it near the toilet and moisten the paper towel.” Regular toilet paper is usually too flimsy to stand up to a soaking, while normal paper towels are too harsh for rectal purposes. Viva is apparently just right. (And no, Asbury is not a brand ambassador, nor does Kleenex endorse this alternative use.)

This advice does come with a major caveat: Viva wipes are not flushable and might very well clog your pipes if you try to send them down the drain.

From Shape:

When it comes to wiping, less is more and not just because it keeps you from replacing the toilet paper roll every other day. “Overwiping can irritate the perianal skin and lead to small abrasions that trigger inflammation and itching,” Sheth [a gastroenterologist] says. One or two wipes are all it takes, he says. If you need to wipe more than that you may not have completely emptied your system or you could be constipated (in which case, up your fiber and water intake like you would to prevent hemorrhoids). If you still require more than a few wipes, consider switching to wet toilet paper or unscented baby wipes. “Moist wipes decrease the friction of wiping and cause less irritation,” Sheth says.

The first two links recommend against baby wipes.

From Sussex Surgery:

Many people cannot bear the thought of a dirty anus and they go to great lengths to keep their anus spotlessly clean using large amounts of toilet paper and vigorously washing the area, especially after defaecation.  Unfortunately this breaks down the fragile anal skin and then this usually effective barrier to bacteria lets in microbes to the surrounding tissues.  This is very irritating to local nerves and people then get in to a viscious cycle because they get itchy, feeling the need to clean the anus even more, which breaks down the anal skin barrier even further.  Therefore it is ironically and usually the cleanest people that end up in my specialist bowel surgery clinic rather than the dirtiest!

The first thing to do is to break the vicious cycle and I recommend that people tone down their anal cleaning routine.  Fingernails and abrasive materials such as rough toilet paper should be kept away from the anus.  Non-scented baby wipes or luxury toilet tissue are usually the kindest and most effective ways of wiping the bottom after opening the bowels.  Running water is the best way to wash the anal surfaces.

Often people think that they must keep on wiping their bottom with toilet paper until they do not see any more brown smears on the toilet paper but this can cause significant damage.  Instead people should stop wiping when the brown smears have lessened but before they rub their fragile anal skin raw.

From Atlas Obscura:

All of this provides a mixed view on the ideal material for wiping. Water is very good, because it’s gentle and won’t cause tears, but you want to stay away from residual moistness. Toilet paper isn’t bad, because it easily soaks up any moisture, but it also can be a little rough, which is bad. The ideal method would probably be a water bath followed by careful, gentle, and immediate drying, whether that’s with toilet paper or a jet of warm air.

For a history of anal hygeine and a tour of various cultures, visit Toilet Guru.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords.com.

 

Red and Processed Meats May Not Be the Killers We Imagined

From New York Times:

Public health officials for years have urged Americans to limit consumption of red meat and processed meats because of concerns that these foods are linked to heart disease, cancer and other ills.

But on Monday, in a remarkable turnabout, an international collaboration of researchers produced a series of analyses concluding that the advice, a bedrock of almost all dietary guidelines, is not backed by good scientific evidence.

Whew…What a relief! Dodged that bullet.

Click for Gina Kolata’s article.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com

Use It or Lose It: Fitness Deteriorates With Just Two Weeks of Laziness

exercise for weight loss and management, dumbbells

At least he’s trying…

From UPI:

A new study proves that the old adage “use it or lose it” is definitely true when it comes to fitness.After just two weeks of sedentary behavior, formerly fit people had:

—A decline in heart and lung health

—Increased waist circumference

—Greater body fat and liver fat

—Higher levels of insulin resistance

Source: Study: Two weeks of no exercise enough to damage fit people’s bodies – UPI.com

It’s a small study, just 28 subjects, so may not be reproducible. But I bet it’s reliable.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

This life-changing book has an entire chapter on exercise. Click the pic to purchase at Amazon.com

 

Nuts May Prevent Age-Related Weight Gain

Remember…peanuts aren’t nuts, they’re legumes

From NPR:

Eating a handful of almonds, walnuts, peanuts or any type of nut on a regular basis may help prevent excessive weight gain and even lower the risk of obesity, new research suggests.

It may be that substituting healthy nuts for unhealthy snacks is a simple strategy to ward off the gradual weight gain that often accompanies aging, according to the researchers. Nuts also help us feel full longer, which might offset cravings for junk food.Researchers looked at the diet and weight of more than 280,000 adults taking part in three long-term research studies. Over more than 20 years of monitoring, participants were asked every four years about their weight and, among other things, how often, over the preceding year, they had eaten a serving (about one ounce) of nuts.

Source: Just A Handful Of Nuts May Help Keep Us From Packing On The Pounds As We Age : The Salt : NPR

Steve Parker, M.D.

PS: Both of my Mediterranean Diets include nuts.

Steve Parker MD, Advanced Mediterranean Diet

Is Rapamycin the Holy Grail of Anti-Aging Medicine?

MRI of brain

Rapamycin may prevent chronic age-related diseases like Alzheimer’s Disease. From P.D. Mangan who interviewed Alan S. Greeen, M.D., prescriber and user of the drug himself:

For many informed observers of anti-aging science and practice, rapamycin appears to be one of the most promising anti-aging treatments currently available. Originally (and still) used as an immunosuppressant for transplant patients, it’s been found to increase lifespan in lab animals.

Side effects of rapamycin are a problem, but it’s since been found that a transient (3-month) treatment with rapamycin can extend life expectancy up to 60%. More studies are needed to determine the dosing regimen with maximal efficacy and minimal side effects. Intermittent dosing at once every 5 days also extends lifespan in mice, and this “demonstrates that the anti-aging potential of rapamycin is separable from many of its negative side effects and suggests that carefully designed dosing regimens may permit the safer use of rapamycin and its analogs for the treatment of age-related diseases in humans. ” Note also that this dosing regimen wasn’t started until the mice were quite old, at 20 months, and it still extended lifespan.

The principal mechanism of action of rapamycin is the inhibition of the cellular nutrient sensor and growth regulator mTOR. In elderly humans, weekly dosing of an mTOR inhibitor (not rapamycin) increased immune function as measured by response to a flu vaccine.

Given all of this, rapamycin as it relates to the slowing or reversal of aging, is still an experimental drug. However, we will be waiting a long time, perhaps forever, for the FDA to approve rapamycin for anti-aging, and since it’s a generic drug, there’s little incentive for drug companies to pursue clinical trials. Meanwhile, many people have begun to realize that they could be dead before this treatment becomes recognized – again, if ever.

Source: Rapamycin Anti-Aging Medicine: An Update with Alan S. Green, M.D. – Rogue Health and Fitness

Mangan’s site is a trove of anti-aging strategies.

Steve Parker, MD.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com

Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Cognitive Enhancement and Associated Changes in Cerebrospinal Fluid, Blood, and Brain Imaging 

A) A MemorEMTM head device being worn by a subject. B) Position of the eight electromagnetic emitters embedded between the device’s two-layered head cap. Emitters collectively provide global forebrain TEMT via rapid sequential emitter activation.

This is from the cited journal article. I hope this is considered fair use rather than copyright infringement.

This is the most creative therapeutic approach to Alzheimer’s Disease I’ve seen in a while. It may even be preventative. I have no idea whether it will pan out in the long run. I’m always skeptical.

Click for a Scientific American article that discusses a different experimental protocol and probably different device.

Abstract

Background: Small aggregates (oligomers) of the toxic proteins amyloid-β (Aβ) and phospho-tau (p-tau) are essential contributors to Alzheimer’s disease (AD). In mouse models for AD or human AD brain extracts, Transcranial Electromagnetic Treatment (TEMT) disaggregates both Aβ and p-tau oligomers, and induces brain mitochondrial enhancement. These apparent “disease-modifying” actions of TEMT both prevent and reverse memory impairment in AD transgenic mice.

Objective: To evaluate the safety and initial clinical efficacy of TEMT against AD, a comprehensive open-label clinical trial was performed.

Methods: Eight mild/moderate AD patients were treated with TEMT in-home by their caregivers for 2 months utilizing a unique head device. TEMT was given for two 1-hour periods each day, with subjects primarily evaluated at baseline, end-of-treatment, and 2 weeks following treatment completion.

Results: No deleterious behavioral effects, discomfort, or physiologic changes resulted from 2 months of TEMT, as well as no evidence of tumor or microhemorrhage induction. TEMT induced clinically important and statistically significant improvements in ADAS-cog, as well as in the Rey AVLT. TEMT also produced increases in cerebrospinal fluid (CSF) levels of soluble Aβ1-40 and Aβ1-42, cognition-related changes in CSF oligomeric Aβ, a decreased CSF p-tau/Aβ1-42 ratio, and reduced levels of oligomeric Aβ in plasma. Pre- versus post-treatment FDG-PET brain scans revealed stable cerebral glucose utilization, with several subjects exhibiting enhanced glucose utilization. Evaluation of diffusion tensor imaging (fractional anisotropy) scans in individual subjects provided support for TEMT-induced increases in functional connectivity within the cognitively-important cingulate cortex/cingulum.

Conclusion: TEMT administration to AD subjects appears to be safe, while providing cognitive enhancement, changes to CSF/blood AD markers, and evidence of stable/enhanced brain connectivity.

Source: A Clinical Trial of Transcranial Electromagnetic Treatment in Alzheimer’s Disease: Cognitive Enhancement and Associated Changes in Cerebrospinal Fluid, Blood, and Brain Imaging – IOS Press

Steve Parker, M.D.

PS: I notice that several of the study authors are based in my area of operations, south-central Arizona.

PPS: The Mediterranean diet for years has been linked to lower risk of dementia.

Steve Parker MD, Advanced Mediterranean Diet

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High-Dose Vitamin D Supplementation May Be Worse or No Better Than Low-Dose

Lately I’m seeing more patients taking high-dose vitamin D supplements (usually D3, aka cholecalciferol) rather than traditional 400–800 IU/day.

From a recent study:

This randomized trial compares the effects of 400 vs 4000 vs 10 000 IU of vitamin D on total volumetric bone mineral density and bone strength of the radius and tibia.

Conclusion:

Among healthy adults, treatment with vitamin D for 3 years at a dose of 4000 IU per day or 10 000 IU per day, compared with 400 IU per day, resulted in statistically significant lower radial BMD; tibial BMD was significantly lower only with the 10 000 IU per day dose. There were no significant differences in bone strength at either the radius or tibia. These findings do not support a benefit of high-dose vitamin D supplementation for bone health; further research would be needed to determine whether it is harmful.

Source: Effect of High-Dose Vitamin D Supplementation on Volumetric Bone Density and Bone Strength: A Randomized Clinical Trial | Osteoporosis | JAMA | JAMA Network

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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Animal Versus Plant Protein: Which Is Healthier?

Filet mignon and sautéed asparagus

“In this large prospective study, higher plant protein intake was associated with lower total and CVD-related mortality. Although animal protein intake was not associated with mortality outcomes, replacement of red meat protein or processed meat protein with plant protein was associated with lower total, cancer-related, and CVD-related mortality.”

Source: Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality | Cardiology | JAMA Internal Medicine | JAMA Network

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com

Soft Drinks Kill

Green tea is not linked to premature death

The study at hand involved Europeans. It’s the first time I’ve seen artificially-sweetened soft drinks linked to premature death.

From JAMA Network:

This study found that consumption of total, sugar-sweetened, and artificially sweetened soft drinks was positively associated with all-cause deaths in this large European cohort; the results are supportive of public health campaigns aimed at limiting the consumption of soft drinks.

Source: Association Between Soft Drink Consumption and Mortality in 10 European Countries | Cardiology | JAMA Internal Medicine | JAMA Network

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com

Does Calcium  Intake Affect Postmenopausal Osteoporosis or Osteopenia?

Waste of money and effort?

Many physicians worry that inadequate calcium consumption causes or contributes to thin, brittle, easily breakable bones in postmenopausal women. A recent study suggests that calcium intake doesn’t matter.

Abstract

CONTEXT:

Calcium intakes are commonly lower than the recommended levels, and increasing calcium intake is often recommended for bone health.

OBJECTIVE:To determine the relationship between dietary calcium intake and rate of bone loss in older postmenopausal women.

PARTICIPANTS:

Analysis of observational data collected from a randomized controlled trial. Participants were osteopenic (hip T-scores between -1.0 and -2.5) women, aged >65 years, not receiving therapy for osteoporosis nor taking calcium supplements. Women from the total cohort (n = 1994) contributed data to the analysis of calcium intake and bone mineral density (BMD) at baseline, and women from the placebo group (n = 698) contributed data to the analysis of calcium intake and change in BMD. BMD and bone mineral content (BMC) of the spine, total hip, femoral neck, and total body were measured three times over 6 years.

RESULTS:

Mean calcium intake was 886 mg/day. Baseline BMDs were not related to quintile of calcium intake at any site, before or after adjustment for baseline age, height, weight, physical activity, alcohol intake, smoking status, and past hormone replacement use. There was no relationship between bone loss and quintile of calcium intake at any site, with or without adjustment for covariables. Total body bone balance (i.e., change in BMC) was unrelated to an individuals’ calcium intake (P = 0.99).

CONCLUSIONS:

Postmenopausal bone loss is unrelated to dietary calcium intake. This suggests that strategies to increase calcium intake are unlikely to impact the prevalence of and morbidity from postmenopausal osteoporosis.

Source: Dietary Calcium Intake and Bone Loss Over 6 Years in Osteopenic Postmenopausal Women. – PubMed – NCBI

Steve Parker, M.D.

PS: Elderly men get osteoporosis, too. But when the Emergency Department calls me to admit an older patient with a hip fracture, it’s a woman 9 out of 10 times.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com