Alcohol and Cancer Risk: Clinical and Research Implications | Oncology | JAMA | JAMA Network

Stillhouse Moonshine Whiskey (NOT specifically linked to increased cancer risk)

Do you drink alcohol in part because you think it’s good for heart health? For longevity? To prevent dementia? If so, you may be increasing your risk of cancer.

From JAMA Network:

Ample evidence has been available for some time indicating that alcohol use is a preventable risk factor for cancer, and the World Health Organization deemed alcohol a carcinogen more than 30 years ago. In the United States, it is estimated that 5.6% of incident cancer cases (approximately 87 000 each year) are associated with alcohol, including cancers of the oral cavity, pharynx, larynx, liver, esophagus (squamous cell carcinoma), female breast, and colorectum. Type of alcohol does not appear to matter; all alcoholic beverages include ethanol, which increases levels of acetaldehyde and in turn promotes DNA damage. Moreover, even moderate levels of consumption (often defined as approximately 14–28 g/d, the equivalent of about 1–2 drinks) appear to be associated with higher risk of some cancers, including cancers of the female breast. A protective association has emerged for some cancers, with the most evidence for kidney, Hodgkin lymphoma, and non-Hodgkin lymphoma. Nonetheless, the overall cancer burden associated with alcohol use is substantial and comparable with that of other preventable risk factors such as UV exposure and excess body weight.

Source: Alcohol and Cancer Risk: Clinical and Research Implications | Oncology | JAMA | JAMA Network

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Is Type 2 Diabetes Caused by Ultra-Processed Foods?

 

One example of UPF

A recent observational study done in France found an association between incidence of type 2 diabetes and consumption of ultra-processed foods.

What are ultra-processed foods? From the study at hand, “Ultraprocessed foods (UPF) (ie, foods undergoing multiple physical, biological, and/or chemical processes, among which mostly of exclusive industrial use, and generally containing food additives) are widespread worldwide and especially in Western diets, representing between 25% and 60% of total daily energy [calories].”

These results suggest an association between UPF consumption and type 2 diabetes risk. They need to be confirmed in large prospective cohorts in other settings, and underlying mechanisms need to be explored in ad hoc epidemiological and experimental studies. Beyond nutritional factors, nonnutritional dimensions of the diet may play a role in these associations, such as some additives, neoformed contaminants, and contact materials. Even if a causal link between UPF and chronic diseases cannot be established so far, the accumulation of consistent data leads public health authorities in several countries such as France or Brazil to recommend privileging the consumption of unprocessed/minimally processed foods, and limiting the consumption of UPF in the name of the precautionary principle.

Source: Ultraprocessed Food Consumption and Risk of Type 2 Diabetes Among Participants of the NutriNet-Santé Prospective Cohort | Lifestyle Behaviors | JAMA Internal Medicine | JAMA Network

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Paul Ingraham Versus Dr John Sarno on Low Back Pain

I read Sarno’s Healing Back Pain many years ago. I’ve mentioned Sarno on this blog at least once. Sarno claims to alleviate many medical problems with his psychological approach. Whenever my wife or I get a migraine or flare of low back pain, we jokingly refer to is as “repressed anger.” Dr Sarno helped Dr Stephan Guyenet (PhD) with his low back pain.

From Paul Ingraham:

Sarno is articulate and has some important ideas, yes — but he’s also gotten into the business of selling miracle cures. The more recent the book, the less he sounds like a doctor and the more he reads like a mind-body medicine guru trying to convince you that you can heal anything if you can just master the right mental attitude.

Yuck. I don’t care for that. I don’t like it any better than I like the opposite extreme: denying the importance of the mind in medicine is just as foolish as exaggerating it.

History has shown us that it is all too easy to sell books by promising that the “power of the mind” can do whatever you want to believe it can do. Sarno has jumped on that old bandwagon. And so, unfortunately, it is not possible for a serious thinker to take Sarno at his word straight through his books. It is necessary to take the good, and filter out the exaggerated, the grandiose, the empty promises.

Source: Critical Analysis Review of Dr. John Sarno’s Books & Ideas

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Dr Gorski on Dr Joseph Mercola: Not a Fan

 

“Would I lie to you if my income depended on it?”

I’m probably on the opposite end of the political spectrum from Dr Gorski, but from a science-based medical perspective I almost always agree with him.

From Dr G at Science-Based Medicine:

One of the most frequent ad hominem attacks leveled against those of us who try to educate the public about medical quackery, antivaccine pseudoscience, and the infiltration of pseudoscience and quackery into medicine in the form of “complementary and alternative medicine” (CAM) or “integrative medicine” is that we’re shills for big pharma. It’s such a common attack that I even coined a phrase to describe it. (Well, I think I coined the phrase; I could be wrong.) It’s known as the “pharma shill gambit.” The idea is as obvious as it is trite: to cast doubt on what defenders of science say about medical quackery by portraying them as in the pocket of big pharma. My frequent retort goes along the lines of, “Dammit, where is all filthy lucre I’m supposed to be getting doing this? Where is my mansion? Where is my Maserati?” Of course, I have none of these things. Don’t get me wrong. As an academic surgeon I make considerably more than the average person, but I’m just well off, not wealthy, and I don’t even make that much compared to the average surgeon in private practice with my level of experience. (Hell, I don’t even make as much as the radiologists at my hospital.) The point is, no one gets wealthy opposing pseudoscience. They do, however, become wealthy selling pseudoscience, as a recent Washington Post story about Dr. Joseph Mercola demonstrates.

Source: “Natural health” and the antivaccine movement: The case of Dr. Joseph Mercola – Science-Based Medicine

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Moderate Wine Consumption May Prevent Dementia

…according to an article at Revue Neurologique:

The inverse relationship between moderate wine drinking and incident dementia was explained neither by known predictors of dementia nor by medical, psychological or socio-familial factors. Considering also the well documented negative associations between moderate wine consumption and cardiovascular morbidity and mortality in this age group, it seems that there is no medical rationale to advise people over 65 to quit drinking wine moderately, as this habit carries no specific risk and may even be of some benefit for their health. Advising all elderly people to drink wine regularly for prevention of dementia would be however premature at this stage.

But: alcohol is linked to higher risk of breast cancer

Source: Wine consumption and dementia in the elderly: a prospective community study in the Bordeaux area. – PubMed – NCBI

“Moderate wine consumption” typically more than 1 glass a day for women, no more then two for men.

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Like Last Year, Flu Vaccine Not as Effective as Wished

From LiveScience:

“There’s more bad news about the flu: The main strain of flu that’s circulating right now doesn’t exactly match what’s in this year’s flu shot, according to a new report.

However, the strain in the vaccine may still be close enough to offer some protection, officials said.”

Source: This Year’s Flu Shot Doesn’t Match What’s Circulating. Here’s What That Means. | Live Science

Intermittent Fasting Is Probably Good For You

Eating within a 10-hour window shouldn’t be too hard. Breakfast at 7 AM, finish dinner by 5 PM. That’s right, we don’t need to be eating every 3–4 hours. Do you think our ancestors over the last 200,000 years have been eating three meals a day? I don’t. The probably went 24–48 hrs without much food on a regular basis.

From LA Times:

In an early effort to explore the benefits of daily fasting in humans, researchers have found that people who are at high risk of developing diabetes improved their health in myriad ways when they ate all of their meals over a span of just over 10 hours, then fasted for the remainder of their 24-hour day.

Source: Variant of intermittent fasting improved health in new study – Los Angeles Times

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

What’s the Best Approach to Fatty Liver (Hepatic Steatosis)?

Excessive accumulation of fat in the liver can lead to liver inflammation and ultimately liver failure. Trust me, you don’t want liver failure.

For years, the mainstays of treatment for fatty liver has been loss of excess weight and alcohol abstention.

From Dr Bret Scher at DietDoctor:

Fortunately, we have emerging evidence that low-carb and ketogenic diets improve fatty liver while also helping with glycemic control and weight loss, an impressive combination rarely seen with medications. As we reported earlier, studies have shown that carbohydrate restriction changes liver metabolism, stimulating the breakdown of liver fat. Another study mentioned in the same post showed that when children substitute complex forms of starch to replace sugar, they experience reduced amounts of liver fat.

Yet another impressive study found that despite equal weight loss, a low-carb Mediterranean diet was better than a low-fat diet for reversing liver fat and signs of NAFLD. And finally, Virta Health published a subset of its data showing that one year on a ketogenic diet improved non-invasive tests for NAFLD and liver scarring.

Source: Limiting Carbs Likely Better Than Drugs for Fatty Liver — Diet Doctor

Steve Parker, M.D.

PS: The Advanced Mediterranean Diet book includes the very low-carb Ketogenic Mediterranean Diet.

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.

Probably under $12 at Amazon.com in the U.S.

QOTD: Paul Craig Roberts on Truth-Telling

The problem with truth is that it seldom supports establishment interests. Thus, truth is in the way of material and selfish interests of the powerful. That is why it is hard to defend truth and why so few do so. To tell the truth is extremely costly.

Paul Craig Roberts in 2020

 

Why Is Healthcare So Expensive in the U.S.?

U.S. healthcare needs to be resuscitated

The U.S. has a presidential and other federal elections later this year. So we’ll be hearing more talk about healthcare reform. Mostly talk, not much action. Healthcare is an issue because it soaks up 18% of GDP (Gross Domestic Product). Many of us think that’s way too much and we can’t afford it anymore. Most other fully developed Western nations spend 9–11% of GDP on healthcare. Are we in the U.S. getting our money’s worth? Probably not, if you look at things like longevity, infant mortality rates, and overall disease burden.

When I aim to cure a disease, it helps immensely if I know the cause of the disease. That determines the treatment plan. If we want to fix over-spending on healthcare, we need to know the causes. With the right treatment plan, we might get healthcare costs down to 5% of GDP.

Here are the causes of overly-expensive healthcare:

  • Lack of price transparency
  • Third-party payer between patient and provider (they must be paid). Third party may not care about cost; just pass it on via premiums, or insulate themselves via high deductibles.
  • Defensive Medicine: excessive testing and consultations, malpractice insurance premiums, time away from patient care
  • Excessive regulation
  • Government essentially mandates Emergency Department care regardless of ability to pay
  • Excessive administrative costs (bureaucracy) of a byzantine system: providers’ office, healthcare insurance, hospital administration, regulators
  • Lobbying protects insurers, doctors, hospitals, Big Pharma at the expense of consumers
  • Low or no deductibles (no skin in the game)
  • Little incentive for patient to get or stay healthy
  • Government and insurers pay lousy docs the same fee as good doctors, so no incentive for great care or innovation. If you want to improve healthcare, you must financially reward competent and successful competitors. 
  • Providers are incentivized to provide services: provide more services, earn more pay
  • Greed
  • Insurance mandates
  • Inadequate competition among providers
  • Un-enforced anti-trust and consumer protection laws 
  • Excessive drug costs
  • Over-utilization of specialist care instead of primary care
  • Laws prevent importation of drugs by patients or providers from cheaper markets
  • Insurance companies prohibited from selling across state lines?
  • Pharmacy Benefits Management Co’s?
  • Insurance pays for too much, instead of only catastrophic care?
  • Waste and fraud?
  • Monopolies or near-monopolies (e.g., dominant hospital systems, insurance companies)?
  • Government fee-setting (Medicare and Medicaid)

If I’ve missed anything, please leave it in a comment below or email me at steveparkermd[at]gmail[dot]com.

Steve Parker, M.D.

PS: Below are some interesting links I found while researching this post.

From Investopedia in 2019:

“Even with all this money being spent on healthcare, the World Health Organization ranked the U.S. 37th in healthcare systems, and The Commonwealth Fund placed the U.S. last among the top 11 industrialized countries in overall healthcare.”

 From CNBC.com March 2018:

“The real difference between the American health care system and systems abroad is pricing.”

From JAMA Network March 2018:

“The United States spent approximately twice as much as other high-income countries on medical care, yet utilization rates in the United States were largely similar to those in other nations. Prices of labor and goods, including pharmaceuticals, and administrative costs appeared to be the major drivers of the difference in overall cost between the United States and other high-income countries.”

Yale Insights 2016 report focusing on hospitals:

“This study tells us that insurance premiums are so high because healthcare provider prices are incredibly high. The way to rein in the cost of healthcare services is by targeting the massive variation in providers’ prices. We can do that by making prices more transparent, making these markets more dynamic, and really blunting the monopoly power that a lot of large healthcare providers have, which has allowed them to raise prices.” Interviewee says the hospital industry is 8% of GDP.

PPS: Why not do everything you can to get and stay healthy, hopefully keeping you out of the Medical-Industrial Complex? If you need weight loss and exercise, I can help…

Steve Parker MD, Advanced Mediterranean Diet

Click the pic to purchase at Amazon.com. E-book versions also available at Smashwords. com.