Legalized Recreational #Marijuana Increases Traffic Fatality Rates

“By analyzing additional experimental states over a more recent time period, we have provided additional data that legalization of recreational marijuana is associated with increased traffic fatality rates. Applying these results to national driving statistics, nationwide legalization would be associated with 6800 (95% CI, 4200-9700) excess roadway deaths each year. Despite certain methodological differences, we found an increase similar to that reported by Aydelotte et al. They reported an increase of 1.8 fatal crashes (equivalent to 2.0 fatalities) per BVMT. We concur with their opinion that changes may not be detected immediately after legalization but only after a longer time period or after commercial sales begin.”

Source: Change in Traffic Fatality Rates in the First 4 States to Legalize Recreational Marijuana | Emergency Medicine | JAMA Internal Medicine | JAMA Network

Steve Parker MD, Advanced Mediterranean Diet

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#Hydroxychloroquine Reduced Death Rate Significantly in #COVID19 Patients in Henry Ford Health System 

Intubated to prevent death

DETROIT – Treatment with hydroxychloroquine cut the death rate significantly in sick patients hospitalized with COVID-19 – and without heart-related side-effects, according to a new study published by Henry Ford Health System.

In a large-scale retrospective analysis of 2,541 patients hospitalized between March 10 and May 2, 2020 across the system’s six hospitals, the study found 13% of those treated with hydroxychloroquine alone died compared to 26.4% not treated with hydroxychloroquine. None of the patients had documented serious heart abnormalities; however, patients were monitored for a heart condition routinely pointed to as a reason to avoid the drug as a treatment for COVID-19.

The study was published today in the International Journal of Infectious Diseases, the peer-reviewed, open-access online publication of the International Society of Infectious Diseases (ISID.org).

Patients treated with hydroxychloroquine at Henry Ford met specific protocol criteria as outlined by the hospital system’s Division of Infectious Diseases. The vast majority received the drug soon after admission; 82% within 24 hours and 91% within 48 hours of admission. All patients in the study were 18 or over with a median age of 64 years; 51% were men and 56% African American.

Source: Treatment with Hydroxychloroquine Cut Death Rate Significantly in COVID-19 Patients, Henry Ford Health System Study Shows | Henry Ford Health System – Detroit, MI

I had trouble finding  a link to the primary research article.

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Have You Heard of the Three C’s to Prevent a Second Wave of #COVID19 ?

I’m ready for the 2nd wave in AZ

From Calculated Risk:

Some countries have been able to open their economies without an increase in [coronavirus] infections. For example, in Japan, the economy is mostly open, however 1) everyone wears a mask, 2) there is robust contact tracing, and 3) everyone is urged to follow the 3 C’s (avoid Closed spaces, Crowded places, and Close-Contact settings).   However, in the US, contact tracing is still ramping up, many people aren’t wearing a mask or face covering, and many people are not following the 3Cs.

Source: Calculated Risk: Economic Outlook: The Gathering Storm

Steve Parker MD, Advanced Mediterranean Diet

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Recommended Movie: #Blindspotting

U.S. Daily #COVID19 Deaths

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QOTD: David Burge and Kathy Shaidle On Manifestos

Modern Unabomber?

David Burge (@iowahawkblog) on Twitter, June 27, 2020:
By and large, anyone who publishes a “manifesto” should be hospitalized for psychiatric evaluation

To which Kathy Shaidle commented:

I’m in general agreement, because with very few exceptions, most “manifestos” are a contradiction in terms.

By definition, they are written to arouse outrage and action amongst the general population, but are more frequently just a record of someone talking to themselves. The Unabomber’s manifesto would never have been published if he hadn’t killed a bunch of people….

When I finish my U.S. healthcare reform white paper, I think I’ll call it a manifesto.

Note the Trend In #COVID19 Deaths In US

From covidtracking.com

 

QOTD: A Minority Opinion On the Mask

Probably at little risk of serious illness if she’s generally healthy

The Slave is terrified of death. He yearns to obey authority figures. The Free man loathes the face mask, tries to push back thoughts about it being a muzzle-like humiliation ritual, to have to put one on at a store. I keep a scintilla of my humanity by folding a bandana into a triangle and tying it behind my head rather than having one of those face-cupping masks, which resemble the front part of men’s briefs.

The Slave fears death because he is an atheist. The Free man is nonchalant on the concept of death, especially when he’s not entirely convinced that the health-risk is real, because knows that there is a life beyond. So he sees no reason to cling to physical security past the point where personal dignity comes into play.

Source: The face mask – PA

ACE Inhibitors Not a Risk Factor for #COVID19 #Coronavirus

Probably at little risk of serious illness if she’s generally healthy

Early on in this pandemic, there was concern that people taking ACE inhibitor drugs for hypertension would be more prone to infection from the coronavirus SARS-CoV-2. From two new studies in NEJM:

In this large, population-based study, the use of ACE inhibitors and ARBs was more frequent among patients with Covid-19 than among controls because of their higher prevalence of cardiovascular disease. However, there was no evidence that ACE inhibitors or ARBs affected the risk of COVID-19.

Source: Renin–Angiotensin–Aldosterone System Blockers and the Risk of Covid-19 | NEJM

We found no substantial increase in the likelihood of a positive test for Covid-19 or in the risk of severe Covid-19 among patients who tested positive in association with five common classes of antihypertensive medications [including ACE inhibitors and ARBs].

Source

 

How Much Calcium Do You Need for Strong Bones?

paleo diet, Steve Parker MD,calcium, osteoporosis

Milk is a common source of calcium

I don’t know, and I’m not sure anybody else does.

The biggest concern about inadequate calcium consumption is that your bones will be weak and brittle, leading to fractures.

Dr Harriet Hall at Science Based Medicine reviewed a NEJM article written by Drs Willets and Ludwig on the health effects of milk.

From Dr Hall:

I was surprised to learn that the US recommendations for milk consumption were based on small, flawed studies of calcium balance. Other countries recommend lower levels of calcium intake. The US recommends 1000-1200 mg for adults, the UK 700 mg, and the World Health Organization, 500 mg. Counterintuitively, countries with high milk and calcium intake actually have the highest rates of hip fracture. Clinical trials of calcium for fracture prevention are complicated, because of confounding factors like vitamin D, phosphorous, and adult height. High calcium intake during childhood and adolescence was thought to serve as a way to “bank” calcium, but studies have not supported that hypothesis. In fact, men’s risk of hip fracture increased by 9% for every additional glass of milk consumed during adolescence.

Source: Milk and Health: The Evidence – Science-Based Medicine

Steve Parker, M.D.

Steve Parker MD, Advanced Mediterranean Diet

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