Category Archives: Uncategorized

Have You Heard of “Dry January”?

See you in February. Or not.

I’ve run across a number of people who slowly increased their alcohol consumption over months or years, not realizing it was causing or would cause problems for them. Alcohol is dangerous, lethal at times.

From a health standpoint, the generally accepted safe levels of consumption are:

  • no more than one standard drink per day for women
  • no more than two standard drinks per day for men

One drink is 5 ounces of wine, 12 ounces of beer, or 1.5 ounces of 80 proof distilled spirits (e.g., vodka, whiskey, gin).

Dry January was conceived in the UK in 2012 or 2014. (A related concept is Sober October.) The idea is simply to abstain from all alcohol for the month of January. The Alcohol Change UK website can help you git ‘er done. Many folks notice that they sleep better, have more energy, lose weight, and save money. There are other potential benefits.

If you think you may have an unhealthy relationship with alcohol, check your CAGE score. It’s quick and easy.

Alternatively, if you make a commitment to a Dry January but can’t do it, you may well have a problem.

Steve Parker, M.D.

United Healthcare’s CEO Murdered In Cold Blood

Bob Lefsetz is a music industry journalist blogger that I follow regularly although not reading every post. He lives in the Los Angeles area. He wrote recently about the apparent execution of United Healthcare’s 50-year-old CEO in NYC:

And we thought the revolution would arrive as a result of the red/blue divide. When in truth, it’s all about income inequality.

Please don’t criticize me for having sympathy for those screwed by the insurance companies. If I were in charge, there’d be no guns at all, or a law akin to that in Australia. But one would posit that the shooter is pissed because the insurance company didn’t pay.

But that’s what insurance companies do, not pay. That’s their business model. Even assuming you can see the doctor of your choice, which is rare. As a matter of fact, essentially all my doctors in L.A. don’t take insurance at all. You pay the freight, which ain’t inexpensive. And why did these MDs stop taking insurance? Because the insurance companies were running them ragged.

And then there are the hospitals… If you can even find an independent doctor… Everybody is now part of a giant organization, which squeezes the physicians. My dermatologist couldn’t sleep. She was on the edge of giving up practice, because at Cedars they required her to see an inordinate number of patients per hour. And this is the only doctor who could diagnosis my pemphigus, even the supposed biggest guy in L.A. couldn’t. She didn’t insist that I follow her into private practice, but for me it’s a no-brainer.

And my internist… He left the UCLA system and it was like he had a personality transplant. Instead of being harried and short, he’s folksy, talks music, and is unbelievably thorough. He diagnosed my leukemia. Do you really think I’m going to go back to the factory?

Although we don’t yet know much about the shooter’s motive, Bob ties the murder to the U.S. healthcare system.

Steve Parker, M.D.

What’s Really Happening in Gaza?

Is this documentary the truth or propaganda? You decide. Just don’t ignore this issue, which could lead to WW3. Most of the mainstream media coverage in the U.S. slants it in Israel’s favor. This is the other side.

That’s Just Great: Harmful Chemicals Contaminate Fruits and Vegetables

Strawberry Food” by Suzy Hazelwood/ CC0 1.0

Fruits and veggies are good for us, right. We should eat more more of them, right?

UK’s Daily Mail published a worrisome article about pesticide residues (PFAS) on many fruits and veggies: strawberries, grapes, cherries, spinach, tomatoes, peaches/nectarines, etc. The tested foods were from UK supermarkets but I bet the numbers are just as bad or worse in the U.S. PFAS stands for per- and polyfluoroalkyl substances. These man-made and long-lasting chemicals are implicated in causation of cancer, immunity impairment, infertility, impaired kidney function, thyroid disease, and low birth weight.

Thrice in the last six months I’ve heard that compared to the European Union, U.S. regulators allow many more chemical contaminants in food. That sounds like a deep and circuitous rabbit hole that I’m not ready to explore. Please mention in the comments an authoritative book or website on the subject.

I’ve been trying to grow food here in the Sonoran Desert for the last three years. I’m about ready to give up. My primary pests have been mealy bugs, caterpillars, mice, pack rats, and squirrels.

Steve Parker, M.D.

War Pigs Salivating as Middle East Heats Up

Livin’ the Dream…

I tried to find the origin of “livin’ the dream” once. No luck. I hear someone say it every couple months.

Steve Parker, M.D.

My Nominee for Word of the Year 2024: Stochastic

Around New Year’s Day annually, you see articles or news reports on Word of the Year as chosen by various organizations. E.g., Merriam-Webster’s WOTY for 2023 was “authentic.” Runners up included “rizz” and “deadname.” WOTY for 2022 was one I’ve enjoyed for several years: “gaslighting.”

I read “stochastic” at a blog w/in the last few days. I had heard or read it before but had to look up its meaning. It’s rarely if ever used by the crowd I run with. I thought it had something to do with science, maybe chemistry. The definition from Merriam-Webster:

  • 1) RANDOM. Specifically, involving a random variable
  • 2) PROBABLISTIC; involving chance or probablility

When I read “stochastic” the other day, it was in the term “stochastic terrorism.” I thought the writer was just using a highfalutin substitute for “random.” But no, stochastic terrorism is a thing. William M. Briggs (Statistician to the Stars!) recently wrote about it:

Academics at universities, which are the best kind of academics, invented the idea of stochastic terrorism. According to academic James Angove (who with the others cited below may appreciate emails of congratulation on their prescience), in the peer-reviewed paper “Stochastic terrorism: critical reflections on an emerging concept“, stochastic terrorism is… 

…broadly, the idea that influential individuals may demonise target groups or individuals, inspiring unknown actors to take up terroristic violence against them…I understand the phenomenon to be specifically authoritarian in nature, which not only demonises but dehumanises its targets. 

Does that remind you of something that happened in the U.S. July 13, 2024?

Steve Parker, M.D.

New Drug Rezdiffra for Liver Disease

Stages of liver damage. Healthy, fatty, liver fibrosis and cirrhosis

DiabetesDaily informed me of a new drug available for treatment of a liver disease that affects “up to 20% of people with diabetes. But by no means is the disease limited to diabetics (er, “people with diabetes”). The disease is MASH: metabolic dysfunction-associated steatohepatitis, something else I’d never heard of. (Shouldn’t the acronym be MDASH?) The drug is resmetirom, sold in the U.S. as Rezdiffra. Click for the FDA announcement. MASH can lead to liver scarring (fibrosis), which then qualifies the patient for resmetirom. The DiabetesDaily article is well-written and includes alternatives to this new drug.

I’ve long been aware of NASH: non-alcoholic steatohepatitis. THIS is the liver disease target according to the FDA announcement, which states “Rezdiffra is a partial activator of a thyroid hormone receptor; activation of this receptor by Rezdiffra in the liver reduces liver fat accumulation.” Furthermore:

The most common side effects of Rezdiffra included diarrhea and nausea. Rezdiffra comes with certain warnings and precautions, such as drug-induced liver toxicity and gallbladder-related side effects. 

There may be potential significant interaction of this new drug with others, particularly statin cholesterol-lowering drugs.

Color me skeptical. If only because the drug was on the “accelerated approval pathway.” But I’ll keep an open mind.

I’m not sure, but it appears that candidates for the drug will need a liver biopsy showing fibrosis (scarring).

Steve Parker, M.D.

…Listen to the Father’s Voice

Not quite what you were expecting, was it?

Wishing a glorious Father’s Day to all you dads!

Nomad Capitalist Ranks Ireland Among the Four Most Free Countries